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Pan SHANK Mouse anti-Human, Mouse, Rat, Clone: S23b-49, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527633

Catalog No. PIMA527633


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Description

Description

Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Studies suggest that Shank2 is expressed in the neurons of the developing retina, and could play a role in the neuronal differentiation of the developing retina. Other recent studies suggest that the disruption of glutamate receptors at the Shank postsynaptic platform could contribute to the destruction of the postsynaptic density, which underlies the synaptic dysfunction and loss in Alzheimer ft.s disease.
Specifications

Specifications

Pan SHANK
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Q9QX74, Q9UPX8, D3YZU1, Q9Y566, Q4ACU6, Q80Z38, Q9BYB0, Q9JLU4, Q9WV48
Cortactin binding protein 1, Cortactin SH3 domain-binding protein, Cortactin-binding protein 1, CortBP1, CTTNBP1, GKAP/SAPAP interacting protein, GKAP/SAPAP-interacting protein, KIAA1022, Proline rich synapse associated protein 1, Proline-rich synapse-associated protein 1, ProSAP1, SH3 and multiple ankyrin repeat domains protein 2, SHAN2_RAT, SHANK, Shank2, SPANK-3
Mouse
IgG1
100 μg
-20°C
Primary
171093, 210274, 243961, 59312, 50944, 58234, 22941, 78957, 85358
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
S23b-49
Unconjugated
SHANK2
Liquid
Shank1, SHANK2, Shank3
Fusion protein amino acids 84-309 of rat Shank2
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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