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Paprotrain, Tocris Bioscience™

Catalog Number p-4817265
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
57046-73-8
C16H11N3
245.285
YMYYQRZCCKBFBE-MDWZMJQESA-N
paprotrain, z-?-3-pyridinylmethylene-1h-indole-3-acetonitrile, 2z-2-1h-indol-3-yl-3-pyridin-3-yl prop-2-enenitrile
12248889
(Z)-2-(1H-indol-3-yl)-3-pyridin-3-ylprop-2-enenitrile
C1=CC=C2C(=C1)C(=CN2)C(=CC3=CN=CC=C3)C#N
This item is not returnable. View return policy
57046-73-8
C16H11N3
245.285
YMYYQRZCCKBFBE-MDWZMJQESA-N
paprotrain, z-?-3-pyridinylmethylene-1h-indole-3-acetonitrile, 2z-2-1h-indol-3-yl-3-pyridin-3-yl prop-2-enenitrile
12248889
(Z)-2-(1H-indol-3-yl)-3-pyridin-3-ylprop-2-enenitrile
C1=CC=C2C(=C1)C(=CN2)C(=CC3=CN=CC=C3)C#N

Description

Reversible inhibitor of MKLP-2

Reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2) (Ki = 3.4 μM). Inhibits the basal ATPase activity of MKLP-2 (IC50 = 1.35 μM). Exhibits selectivity for MKLP-2 over 12 other members of the kinesin superfamily, including the closely-related MKLP-1. Cell permeable.
Quantity 10 mg
Formula Weight 245.28
Percent Purity >99%
Chemical Name or Material Paprotrain

Safety and Handling

Recommended Storage Store at +4°C
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