Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

PARN Mouse anti-Human, Clone: OTI4E12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526544

Catalog No. PIMA526544


Add to cart

Description

Description

The protein encoded by this gene is a 3 ft.-exoribonuclease, with similarity to the RNase D family of 3 ft.-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

PARN
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O95453
DAN, deadenylating nuclease, deadenylation nuclease, poly(A)-specific ribonuclease (deadenylation nuclease), poly(A)-specific ribonuclease PARN, polyadenylate-specific ribonuclease
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5073
Immunohistochemistry (Paraffin), Western Blot
OTI4E12
Unconjugated
PARN
Liquid
PARN
Human recombit protein fragment corresponding to amino acids 1-266 of PARN produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit