PARP1 Mouse anti-Human, Clone: 5F1, Abnova™
Mouse monoclonal antibody raised against full length recombinant human PARP1.
Manufacturer: Abnova Corporation MAB12896
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq]
|Mouse monoclonal antibody raised against full length recombinant human PARP1.|
|In PBS, pH 7.3 (50% glycerol, 1% BSA, 0.02% sodium azide).|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1:2000) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to full length human PARP1.|
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