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PARP6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 169451AP

Catalog No. 50-173-1282


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Description

Description

Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
Specifications

Specifications

PARP6
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q2NL67, Q6P6P7
PARP 6, PARP6, Poly [ADP ribose] polymerase 6
Rabbit
IgG
150 μL
-20°C
Primary
300759, 56965, 67287
Western Blot
Unconjugated
PARP6
Liquid
Parp6
PARP6 Fusion Protein Ag10556
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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