Invitrogen™ PATE3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102606

Catalog No. PIPA5102606

Description

Antibody detects endogenous levels of total PATE3.

PATE3 (prostate and testis expressed protein 3), also known as PATE-DJ or HEL-127, is a 98 amino acid protein that contains one UPAR/Ly6 domain and belongs to the PATE family. PATE3 is a secreted protein that is expressed in prostate and testis. The gene that encodes PATE3 consists of around 3,490 bases and maps to human chromosome 11p15.5. Chromosome 11, which comprises approximately 4% of the human genome, is considered a gene and disease association-dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Specifications

• Antigen: PATE3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PATE3
• Gene Alias: Acrosomal vesicle protein HEL-127; epididymis-specific ESC112; Gm17365; HEL-127; Pate3; PATE-DJ; PATE-like protein DJ; predicted gene, 17365; prostate and testis expressed 3; prostate and testis expressed DJ; prostate and testis expressed protein 3; secreted TFP/Ly-6/uPAR protein PATE-DJ
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100169851, 100312956, 100361414
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: B3GLJ2, B3GLJ3
• Gene Symbols: PATE3
• Immunogen: A synthesized peptide derived from human PATE3(Accession B3GLJ2), corresponding to amino acid residues Y12-Q62.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov