Thermo Scientific Lab Vision Pax-5, Rabbit Monoclonal Antibody
Take advantage of part of a comprehensive antibody portfolio with the Thermo Scientific Pax-5, Rabbit Monoclonal Antibody.
Manufacturer: Thermo Scientific RM9133R1
Take advantage of part of a comprehensive antibody portfolio with the Thermo Scientific Pax-5, Rabbit Monoclonal Antibody. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.PAX-5 is a B-cell-specific activator protein (BSAP). In the early stages of B cell developmemt, PAX-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20. PAX-5 is expressed primarily in pro-, pre-, and mature B cells, but not in plasma cells. PAX-5 is expressed in most B-cell malignancies (pre-B and mature B cell lymphomas/leukemias). Over 90% of cases are positive for PAX-5 in Hodgkin's lymphoma, lymphoplasmacytic lymphoma, Merkel cell and small cell carcinoma. T-cell lymphomas, myeloma/plasmacytoma and carcinoid tumors are negative for PAX-5.
Host Species: Rabbit
Species Reactivity: Human. Others not tested.
Immunogen: Synthetic peptide derived from the C-terminus of human PAX-5 protein
Molecular Weight: 50kDa
Positive Control: Tonsil
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
|Synthetic peptide derived from the C-terminus of human Pax-5 protein|
|Cancer and Tumor Biology|
|Ready-to-use for IHC (UVLP)|
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