Thermo Scientific™ Lab Vision™ Pax-5, Rabbit Monoclonal Antibody

Take advantage of part of a comprehensive antibody portfolio with the Thermo Scientific™ Pax-5, Rabbit Monoclonal Antibody. 

Manufacturer:  Thermo Scientific™ RM9133R1

Catalog No. RM9133R1

Description

Take advantage of part of a comprehensive antibody portfolio with the Thermo Scientific™ Pax-5, Rabbit Monoclonal Antibody. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

PAX-5 is a B-cell-specific activator protein (BSAP). In the early stages of B cell developmemt, PAX-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20. PAX-5 is expressed primarily in pro-, pre-, and mature B cells, but not in plasma cells. PAX-5 is expressed in most B-cell malignancies (pre-B and mature B cell lymphomas/leukemias). Over 90% of cases are positive for PAX-5 in Hodgkin's lymphoma, lymphoplasmacytic lymphoma, Merkel cell and small cell carcinoma. T-cell lymphomas, myeloma/plasmacytoma and carcinoid tumors are negative for PAX-5.

Host Species: Rabbit

Clone: SP34

Isotype: IgG

Species Reactivity: Human. Others not tested.

Immunogen: Synthetic peptide derived from the C-terminus of human PAX-5 protein

Molecular Weight: 50kDa

Positive Control: Tonsil

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: PAX-5
• Classification: Monoclonal
• Conjugate: Unconjugated
• Format: Prediluted
• Immunogen: Synthetic peptide derived from the C-terminus of human Pax-5 protein
• Quantity: 1mL
• Research Discipline: Cancer and Tumor Biology
• Primary or Secondary: Primary
• Target Species: Human

• Applications: Immunohistochemistry (Paraffin)
• Clone: SP34
• Formulation: Ready-to-use for IHC (UVLP)
• Host Species: Rabbit
• Isotype: IgG
• Regulatory Status: IVD
• Type: Primary
• Monoclonal or Polyclonal: Monoclonal