Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Pax6 Mouse, Clone: PAX6/496, Novus Biologicals™
Mouse Monoclonal Antibody has been used in 1 publication
Supplier: Novus Biologicals NBP2328930.02MG
SDSDocumentsProduct Certifications Promotions
DescriptionPax6 Monoclonal specifically detects Pax6 in Human, Mouse, Rat, Chicken samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular).
|PBS with 0.05% BSA. with 0.05% Sodium Azide|
|keratitis), MGC17209, Oculorhombin, paired box 6, paired box protein Pax-6|
|Cellular Markers, Diabetes Research, Neuronal Stem Cell Markers, Neuroscience, Sensory Systems, Stem Cell Markers, Stem Cells, Transcription Factors and Regulators, Vision|
|Human, Mouse, Rat, Chicken|
|Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence|
|Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml|
|Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein|
|Protein A purified|
|Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.|
|Store at 4C.|
Provide Content Correction
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok