Mouse anti-Pax7, Clone: SPM613, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2445890.1MG
Ensure accurate, reproducible results in Immunohistochemistry (Paraffin)Pax7 Monoclonal antibody specifically detects Pax7 in Human samples. It is validated for Immunohistochemistry-Paraffin.
|10mM PBS and 0.05% BSA with 0.05% Sodium Azide|
|Recombinant fragment (aa300-600) of human PAX7 protein|
|Apoptosis, Mesenchymal Stem Cell Markers, Stem Cell Markers|
|Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml|
|FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2|
|Protein A or G purified|
|Store at 4C.|
|The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).|
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