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Thermo Scientific™ Lab Vision™ Paxillin Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Paxillin Ab-1, Mouse Monoclonal Antibody.

Specifications

Antigen Paxillin Ab-1
Clone 5H11
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Conjugate Unconjugated
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Products 3
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS404R1
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Thermo Scientific™
MS404R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS404P
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Thermo Scientific™
MS404P
Purified Ab with BSA and Azide 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS404P1
View Documents
Thermo Scientific™
MS404P1
Purified Ab with BSA and Azide 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ Paxillin Ab-1, Mouse Monoclonal Antibody.

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Host Species: Mouse

Clone: 5H11

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Purified recombinant full-length human paxillin protein

Molecular Weight: 68kDa

Positive Control: HeLa cells, Colon CA

Cellular Localization: Membrane and cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Paxillin Ab-1
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RUO
Primary
IgG2a kappa
5H11
Monoclonal
Murine
Cytoskeletal Protein
Purified recombinant full-length human paxillin protein
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