Tocris Bioscience PB 28 dihydrochloride
High affinity σ2 agonist
Manufacturer: Tocris Bioscience 2562/10
DescriptionHigh affinity σ 2 receptor agonist (K i values are 0.8 and 15.2 nM for σ 2 and σ 1 receptors respectively) that displays minimal affinity at other receptors. Inhibits electrically evoked twitch in guinea pig bladder and ileum (EC 50 values are 2.62 and 3.96 µM respectively). Displays antiproliferative and cytotoxic effects in SK-N-SH neuroblastoma and C6 glioma cells.
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|Observed MW: 443.5|
|Soluble to 20mM with gentle warming in water|
Safety and Handling
Recommended Storage : Desiccate at +4°C
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