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  5. Tocris Bioscience™ PB 28 dihydrochloride
  6. 256210

Tocris Bioscience™ PB 28 dihydrochloride

High affinity σ2 agonist

Supplier:  Tocris Bioscience™ 2562/10

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Catalog No. 25-621-0


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Description

Description

PB 28 dihydrochloride is a high affinity σ2 receptor agonist (Ki values are 0.8 and 15.2 nM for σ2 and σ1 receptors respectively) that displays minimal affinity at other receptors. Inhibits electrically evoked twitch in guinea pig bladder and ileum (EC50 values are 2.62 and 3.96 μM respectively). Displays antiproliferative and cytotoxic effects in SK-N-SH neuroblastoma and C6 glioma cells.
Specifications

Specifications

1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine dihydrochloride
>99%
Soluble to 20mM with gentle warming in water
Observed MW: 443.5
172907-03-8
10 mg
C24H38N2O.2HCl
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Safety and Handling

Safety and Handling

Recommended Storage : Desiccate at +4°C

SDS
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