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Tocris Bioscience™ PBIT

JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor

$110.00 - $461.50

Specifications

Chemical Name or Material 2-(4-Methylphenyl)-1,2-benzisothiazol-3(2H)-one
Molecular Formula C14H11NOS
CAS 2514-30-9
Product Type Target: Histone Demethylase Inhibitors
Formula Weight 241.31
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
59-305-0 View Documents Tocris Bioscience™
5930/50
50mg Each for $461.50
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59-301-0 View Documents Tocris Bioscience™
5930/10
10mg Each for $110.00
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Description

Description

JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor (IC50 values are 3, 4.9 and 6 μM for JARID1B, 1A and 1C, respectively). Selective for JARID1 over UTX and JMJD3. Increases levels of methylated H3K4 in JARIDB1-transfected HeLa cells and MCF7 cells. Inhibits proliferation of breast cancer cell lines expressing high levels of JARIDB1.
Specifications

Specifications

2-(4-Methylphenyl)-1,2-benzisothiazol-3(2H)-one
2514-30-9
241.31
C14H11NOS
Target: Histone Demethylase Inhibitors
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

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