Invitrogen™ PBK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578536

Catalog No. PIPA578536

Description

Positive Control: 293T, A431, HeLa, HepG2, U87-MG, SK-N-SH, IMR32, SK-N-AS Predicted Reactivity: Mouse (90%), Rat (93%), Pig (93%), Chimpanzee (99%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PBK (TOPK) is a serine/threonine kinase that is related to the dual specific mitogen-activated protein kinase (MAPKK). The kinase is up-regulated in a variety of hematological malignancies, participates in activating lymphoid cells, and supports testicular function (spermatogenesis). Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

Specifications

• Antigen: PBK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PBK
• Gene Alias: 2810434B10Rik; AW538537; Cancer/testis antigen 84; CT84; D14Ertd732e; epididymis luminal protein 164; HEL164; Lymphokine-activated killer T-cell-originated protein kinase; MAPKK-like protein kinase; Nori-3; PBK; PDZ binding kinase; PDZ-binding kinase; serine/threonine protein kinase; spermatogenesis-related protein kinase; SPK; T-LAK cell-originated protein kinase; TOPK
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55872
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q96KB5
• Gene Symbols: PBK
• Immunogen: Recombinant protein encompassing a sequence within the center of human PBK. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG