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PBX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 182041AP

Catalog No. 50-173-2046


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Description

Description

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1; 19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

PBX1
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P40424, P41778
Homeobox protein PBX1, Homeobox protein PRL, PBX1, pre B cell leukemia homeobox 1, PRL
Rabbit
IgG
150 μL
-20°C
Primary
18514, 304947, 5087
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
PBX1
Liquid
PBX1
PBX1 Fusion Protein Ag12817
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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