PBX1 Mouse anti-Human, Clone: OTI1C11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525580
DescriptionThis gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1; 19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|PBX1; pre-B-cell leukemia homeobox 1; DKFZp686B09108; MGC126627; Pre-B cell leukemia transcription factor-1; pre-B-cell leukemia transcription factor 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of PBX1 produced in HEK293 cell|
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