PBX1b Monoclonal Antibody (CT 41.1), Active Motif™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-3201	Active Motif 61166	10 μg
50-199-3200	Active Motif 61165	100 μg

Description

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1; 19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PBX1b
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene Alias: 2310056B04Rik; D230003C07Rik; DKFZp686B09108; Homeobox protein PBX1; Homeobox protein PRL; MGC126627; OTTHUMP00000032205; PBX homeobox 1; Pbx1; Pbx-1; pre B cell leukemia homeobox 1; pre-B-cell leukemia homeobox 1; Pre-B-cell leukemia transcription factor 1; PRL
• Gene Symbols: PBX1
• Isotype: IgG1 κ
• Purification Method: Protein G
• Product Type: Antibody

• Clone: CT 41.1
• Applications: ChIP Assay, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P40424
• Gene ID (Entrez): 5087
• Immunogen: This PBX1b antibody was raised against a recombinant protein corresponding to amino acids 319 - 347 of human PBX1b.
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: PBX1