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PBX1b Mouse anti-Human, Clone: CT 41.1, Active Motif™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

$116.85 - $356.95

Specifications

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Antigen PBX1b
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3201 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
61166
10 μg
Each for $116.85
Add to cart
 
50-199-3200 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
61165
100 μg
Each for $356.95
Add to cart
 
Description

Description

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1; 19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

Monoclonal
Primary
PBX1b
Unconjugated
SDS
Product Certifications
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