PC4 Polyclonal Antibody, Invitrogen™

Catalog No.	Quantity
PIPA124480	100 μg

Catalog No. PIPA124480

Supplier: Thermo Scientific PA124480

Description

Rabbit Polyclonal Antibody

PA1-24480 detects PC4 in Human samples. PA1-24480 has been successfully used in Western Blot procedures. PA1-24480 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of human PC4. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.

Specifications

• Antigen: PC4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Gene: SUB1
• Gene Accession No.: P53999, P11031, Q63396
• Gene Alias: PC4, TIS7
• Gene Symbols: LOC100686657, SUB1, SUB1A
• Host Species: Rabbit
• Immunogen: Synthetic peptide region of human PC4.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100686657, 10923, 192269, 20024, 479283, 553561
• Target Species: Canine, Fish, Human, Mouse, Rat, Zebrafish
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG