PC4 Mouse anti-Human, Clone: OTI4C10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527146
DescriptionPC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|SUB1 homolog (S. cerevisiae), P15, PC4, p14|
|-20° C, Avoid Freeze/Thaw Cycles|
|Full length human recombit protein of SUB1 produced in E.coli|
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