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PCBP1 Mouse anti-Human, Clone: OTI3D12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526791

Catalog No. PIMA526791


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Description

Description

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular polydomains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5 ft.-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
Specifications

Specifications

PCBP1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q15365
PCBP1; poly(rC) binding protein 1; HNRPE1; HNRPX; hnRNP-E1; hnRNP-X; alpha-CP1; heterogeneous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein X; nucleic acid binding protein sub 2.3
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5093
Immunohistochemistry (Paraffin), Western Blot
OTI3D12
Unconjugated
PCBP1
Liquid
PCBP1
Human recombit protein fragment corresponding to amino acids 1-225 of PCBP1 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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