PCDH11X Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 200701AP
The antibody recognizes isoforms 1 and isoform 6 of PCDH11X. The antibody has no cross reaction to PCDH11Y.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|KIAA1326, PCDH X, PCDH11, PCDH11X, PCDHX, PCDHY, Protocadherin 11, protocadherin 11 X linked, Protocadherin S|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Antigen Affinity Chromatography|
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