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PCDHA3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 188031AP

Catalog No. 50-173-2231


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Description

Description

The antibody can recognize both the isoforms of PCDHA3.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Specifications

Specifications

PCDHA3
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9Y5H8
PCDH alpha 3, PCDH ALPHA3, PCDHA3, protocadherin alpha 3
Rabbit
IgG
150 μL
-20°C
Primary
192163, 56145
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PCDHA3
Liquid
PCDHA3
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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