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PCDHB11 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550725

Catalog No. PA550725


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Description

Description

The antibody detects endogenous levels of total PCDHB11 protein.

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3 ft. exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Specifications

Specifications

PCDHB11
Polyclonal
Unconjugated
PCDHB11
Liquid
PCDHB11
Synthetic peptide corresponding to a region derived from internal residues of human protocadherin beta 11
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
3.1 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q9Y5F2
ME2, PCDH-BETA11
Rabbit
IgG
100 μL
-20°C
Primary
56125
Documents
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