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PCDHGC3 Mouse anti-Human, Mouse, Clone: S174B-27, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527671

Catalog No. PIMA527671


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Description

Description

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Specifications

Specifications

PCDHGC3
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
Q9UN70
PCDHGC3, Cadherin like 2, PC 43, PC43, PCDH 2, PCDH gamma C3, PCDH2, PCDHGC 3, Protocadherin 2, Protocadherin 43, Protocadherin gamma C3, Protocadherin gamma subfamily C 3, Protocadherin2, Protocadherin43, Pcdhgb6
Mouse
IgG1
100 μg
-20°C
Primary
5098, 93706
Immunocytochemistry, Immunofluorescence, Western Blot
S174B-27
Unconjugated
PCDHGC3
Liquid
PCDHGC3
Fusion protein amino acids 720-804 (variable cytoplasmic domain) of mouse Gamma- protocadherin-C3. Human: 97% identity (83/85 amino acids identical). Rat: 97% identity (83/85 amino acids identical). No significant identity with other Gamma-protocadherin proteins.
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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