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PD-1 (CD279) Rabbit anti-Human, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  Invitrogen MA527899

Catalog No. PIMA527899


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Description

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using Recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

CD279 encoded protein is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Specifications

Specifications

PD-1 (CD279)
Recombinant Monoclonal
Unconjugated
PDCD1
Liquid
Rabbit
IgG
100 μl
-20°C
Primary
5133
Immunohistochemistry, Western Blot
RM309
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Q15116
PDCD1
A peptide corresponding to the N-terminus of human PD-1
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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