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  7. PD 135158, Tocris Bioscience™

PD 135158, Tocris Bioscience™

Catalog Number 260850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
130285-87-9
C35H44N4O6
616.759
NNTPEWZUKRSTMM-VVUNRPKCSA-N
4-r-2-r-2-1s,4beta-1,7,7-trimethylbicyclo 2.2.1 heptan-2alpha-yl oxycarbonylamino-2-methyl-3-1h-indol-3-yl propanoylamino-1-phenylethylamino-4-oxobutyric acid
92211238
4-[[(1R)-2-[[(2R)-3-(1H-indol-3-yl)-2-methyl-2-[[(1S,3R,4S)-4,7,7-trimethyl-3-bicyclo[2.2.1]heptanyl]oxycarbonylamino]propanoyl]amino]-1-phenylethyl]amino]-4-oxobutanoic acid
CC1(C2CCC1(C(C2)OC(=O)NC(C)(CC3=CNC4=CC=CC=C43)C(=O)NCC(C5=CC=CC=C5)NC(=O)CCC(=O)O)C)C
This item is not returnable. View return policy
130285-87-9
C35H44N4O6
616.759
NNTPEWZUKRSTMM-VVUNRPKCSA-N
4-r-2-r-2-1s,4beta-1,7,7-trimethylbicyclo 2.2.1 heptan-2alpha-yl oxycarbonylamino-2-methyl-3-1h-indol-3-yl propanoylamino-1-phenylethylamino-4-oxobutyric acid
92211238
4-[[(1R)-2-[[(2R)-3-(1H-indol-3-yl)-2-methyl-2-[[(1S,3R,4S)-4,7,7-trimethyl-3-bicyclo[2.2.1]heptanyl]oxycarbonylamino]propanoyl]amino]-1-phenylethyl]amino]-4-oxobutanoic acid
CC1(C2CCC1(C(C2)OC(=O)NC(C)(CC3=CNC4=CC=CC=C43)C(=O)NCC(C5=CC=CC=C5)NC(=O)CCC(=O)O)C)C

Description

Potent and selective CCK2 antagonist

Potent and selective, nonpeptide CCK2 receptor antagonist (IC50 values are 2.8 and 1232 nM for CCK2 and CCK1 respectively) that displays negligible affinity at GABAA, benzodiazepine, substance P, neurotensin, opioid, bradykinin and 5-HT3 receptors (IC50 > 10 μM). Exhibits anxiolytic activity in elevated plus maze and social interaction tests and increases food intake in rats.
Quantity 50 mg
Formula Weight 616.76
Percent Purity >98%
Chemical Name or Material PD 135158

Safety and Handling

Recommended Storage Store at +4°C
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