Tocris PD 161570
Selective FGFR inhibitor
Manufacturer: Tocris 3724/10
DescriptionSelective FGFR inhibitor (IC50 values are 40, 262 and 3700nM for FGFR, PDGFR and EGFR respectively). Inhibits FGFR receptor phosphorylation (IC50 = 622nM) and growth of A121 cells in vitro.
- Chemical Name: N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
- Formula: C26H35Cl2N7O
- CAS Number: 192705-80-9
- Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
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