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  7. PD 166285 dihydrochloride, Tocris Bioscience™

PD 166285 dihydrochloride, Tocris Bioscience™

Catalog Number 37851
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Quantity:
1 mg
10 mg
This item is not returnable. View return policy
212391-63-4
C26H29Cl4N5O2
585.351
NADLBPWBFGTESN-UHFFFAOYSA-N
6-2,6-dichlorophenyl-2-4-2-diethylamino ethoxy phenyl amino-8-methylpyrido 2,3-d pyrimidin-7 8h-one dihydrochloride, heparin-cantithrombin iii, d04cqg, pd 166285 dihydrochloride, 6-2,6-dichlorophenyl-2-4-2-diethylamino ethoxy phenyl amino-8-methylpyrido 2,3-d pyrimidin-7-one dihydrochloride, 6-2,6-dichlorophenyl-2-4-2-diethylamino ethoxy phenyl amino-8-methylpyrido 2,3-d pyrimidin-7 8h-onedihydrochloride
9916391
6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride
CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl.Cl.Cl
This item is not returnable. View return policy
212391-63-4
C26H29Cl4N5O2
585.351
NADLBPWBFGTESN-UHFFFAOYSA-N
6-2,6-dichlorophenyl-2-4-2-diethylamino ethoxy phenyl amino-8-methylpyrido 2,3-d pyrimidin-7 8h-one dihydrochloride, heparin-cantithrombin iii, d04cqg, pd 166285 dihydrochloride, 6-2,6-dichlorophenyl-2-4-2-diethylamino ethoxy phenyl amino-8-methylpyrido 2,3-d pyrimidin-7-one dihydrochloride, 6-2,6-dichlorophenyl-2-4-2-diethylamino ethoxy phenyl amino-8-methylpyrido 2,3-d pyrimidin-7 8h-onedihydrochloride
9916391
6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride
CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl.Cl.Cl

Description

Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1

Potent inhibitor of the tyrosine kinases c-Src, fibroblast growth factor receptor 1 (FGFR1), and platelet-derived growth factor receptor β (PDGFRβ) (IC50 values are 8.4, 39.3 and 98.3 nM respectively). Also inhibits the checkpoint kinases Wee1 and Myt1; abolishes Cdc2 phosphorylation in numerous tumor cell lines and abrogates the G2 checkpoint.
Quantity 1 mg
Formula Weight 585.35
Percent Purity >99%
Chemical Name or Material PD 166285 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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