Tocris PD 90780
Inhibits NGF binding to p75NTR
Manufacturer: Tocris 5101/10
DescriptionA nonpeptide inhibitor of NGF binding to p75NTR (IC50 ~ 1µM in CHO cells); binds NGF, not p75NTR. Affinity maybe altered by the presence of TrkA receptors. Neuroprotective.
- Chemical Name: 7-(Benzoylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid
- Formula: C19H14N4O4
- CAS Number: 77422-99-2
- Solubility: Soluble to 20mM in 1eq. NaOH with sonication
- Purity: >98
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