Tocris™ PD 90780

Inhibits NGF binding to p75NTR

Manufacturer: Tocris™ 5101/50

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Catalog No. 51-015-0

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For Research Use Only


    Inhibitors PD 90780
    Purity >98
    Molecular Weight 362.34
    Quantity 50mg
    Product Type PD 90780

    A nonpeptide inhibitor of NGF binding to p75NTR (IC50 ~ 1µM in CHO cells); binds NGF, not p75NTR. Affinity maybe altered by the presence of TrkA receptors. Neuroprotective.

    • Chemical Name: 7-(Benzoylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid
    • Formula: C19H14N4O4
    • CAS Number: 77422-99-2
    • Solubility: Soluble to 20mM in 1eq. NaOH with sonication
    • Purity: >98

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