PDE10A Mouse anti-Human, Clone: OTI1B2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524978
DescriptionVarious cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]).
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|HSPDE10A, cAMP and cAMP-inhibited cGMP 3′,5′-cyclic phosphodiesterase 10A, dJ416F21.1 (phosphodiesterase 10A), phosphodiesterase 10A1 (PDE10A1)|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full-length protein expressed in 293T cell transfected with human PDE10A expression vector|
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