PDE1A Mouse anti-Human, Clone: OTI7D5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526610
DescriptionCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|HCAM1, HSPDE1A, 3′,5′ cyclic nucleotide phosphodiesterase, 61 kDa Cam-PDE, calcium/calmodulin-dependent 3′,5′-cyclic nucleotide phosphodiesterase 1A, calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase, calmodulin-dependent phosphodiesterase, cam-PDE 1A, hCam-1, phosphodiesterase-1A|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 259-545 of PDE1A produced in E.coli|
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