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PDE4B Mouse anti-Human, Clone: OTI3A10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525681

Catalog No. PIMA525681


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Description

Description

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specifications

Specifications

PDE4B
Monoclonal
0.73 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q07343
PDE4B; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); RP5-876C12.1; DKFZp686F2182; DPDE4; MGC126529; PDEIVB ; OTTHUMP00000046896; cAMP-specific 3′,5′-cyclic phosphodiesterase 4B; dunce-like phosphodiesterase E4; phosphodiesterase 4B, cAMP-specific; phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E4)
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5142
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI3A10
Unconjugated
PDE4B
Liquid
PDE4B
Full length human recombit protein of PDE4B produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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