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PDE8B Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA131144

Catalog No. PIPA131144

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

PA1-31144 detects PDE8B from rat, human, mouse samples. PA1-31144 has been successfully used in Western blot and imunnoprecipitation applications. The PA1-31144 immunogen is: Synthetic peptide (Human). Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the 5-prime,3-prime-cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been grouped into several families based on substrate affinities, inhibitor sensitivities, mode of regulation, and amino acid sequence homologies. The PDE8 family contains high-affinity cAMP-specific, IBMX (3-isobutyl-1-methyl-xanthine)-insensitive PDEs, such as PDE8B. All PDEs share a conserved C-terminal catalytic region and a variable N-terminal domain that presumably accounts for the distinctive regulatory properties unique to the individual families.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PDE8B
Polyclonal
Unconjugated
O95263, E9Q4S1
PDE8B
Synthetic peptide (Human).
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
Immunoprecipitation, Western Blot
0.6 mg/mL
PDE8B
FLJ11212, PPNAD3
Rabbit
Antigen affinity chromatography
RUO
218461, 309962, 8622
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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