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Thermo Scientific™ Lab Vision™ PDGFRα Ab-1, Rabbit Polyclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.

Manufacturer:  Thermo Scientific™ RB1691P

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Catalog No. RB1691P


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Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.

PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, α and ß coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, alpha while PDGF BB can bind and activate to both PDGFR, α and β

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, and Rat. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide derived from the C-terminus of the precursor form of human PDGFRα

Molecular Weight: ∽190kDa

Postitive Control: Ovarian CA

Cellular Localization: Membrane Specific for PDGFR, α and does not react with PDGFR, β.

Recommended for:

  • Immunohistochemistry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

PDGFR, alpha Ab-1
Polyclonal
1mg/mL
Purified Ab with BSA and Azide
Rabbit
IgG
RUO
Primary
Polyclonal
Immunohistochemistry (Paraffin)
Polyclonal
Unconjugated
Concentrated
A synthetic peptide derived from the C-terminus of the precursor form of human PDGFR, alpha
1mL
Growth Factor
Primary
Human, Murine
SDS
Documents
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