PDGFRA Mouse anti-Human, Biotin, Clone: 16A1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen A15732
DescriptionPDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
|PBS with 15mM sodium azide; pH 7.4|
|PDGF Receptor alpha, MGC74795, PDGFR2, RHEPDGFRA, CD140 antigen-like family member A, CD140a antigen, PDGF-R-alpha, PDGFRA/BCR fusion, pdgfr-a|
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