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PDGFRB Mouse anti-Human, Mouse, Clone: 42G12, Abnova™

Mouse monoclonal antibody raised against human PDGFRB.

Manufacturer:  Abnova Corporation MAB12588

Catalog No. 89-934-750


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Description

Description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq]

Specifications

Specifications

PDGFRB
42G12
Mouse monoclonal antibody raised against human PDGFRB.
In PBS, pH 7.2 (50% glycerol, 0.09% sodium azide).
CD140B/JTK12/PDGF-R-beta/PDGFR/PDGFR1
Mouse
IgG1
50 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human, Murine
Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL) Western Blot The optimal working dilution should be determined by the end user.
Liquid
PDGFRB
Recombinant protein corresponding to human PDGFRB.
Protein G purification
RUO
Primary
5159
SDS
Documents
Product Certifications
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