PDGFRB Mouse anti-Human, Mouse, Clone: 42G12, Abnova™
Mouse monoclonal antibody raised against human PDGFRB.
Manufacturer: Abnova Corporation MAB12588
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq]
|Mouse monoclonal antibody raised against human PDGFRB.|
|In PBS, pH 7.2 (50% glycerol, 0.09% sodium azide).|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL) Western Blot The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to human PDGFRB.|
|Protein G purification|
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