PDIA2 Recombinant Polyclonal Antibody (7HCLC), Invitrogen™

Rabbit Recombinant Polyclonal Antibody

Supplier:  Thermo Scientific 710081

Catalog No. PI710081

Description

Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain. Recombit rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombit monoclonal antibodies, providing the best of both worlds – the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombit antibody. While functionally the same as a polyclonal antibody – recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets – a recombit rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

PDI (ER marker) also known as protein disulfide isomerase is an enzyme present in the ER which plays a very important role in protein folding, by facilitating formation of correct disulphide bonds. Processing and maturation of the secretory proteins in the endoplasmic reticulum are actively done by the family of PDI proteins. This class of proteins show similar homology to the cytoplasmic protein thioredoxin. The protein catalyses the thiol/disulphide interchange interactions. Also depending upon the type of polypeptide substrate and redox potential, the protein brings about protein disulfide formation, isomerization or reduction.

Specifications

• Antigen: PDIA2
• Classification: Recombinant Polyclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: Q13087
• Gene Symbols: PDIA2
• Immunogen: Recombit Protein corresponding to amino acids 378-525 of human PDI (ER Marker).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 7HCLC
• Conjugate: Unconjugated
• Gene: PDIA2
• Gene Alias: Disulphide Isomerase antibody, GIT antibody, Glutathione Insulin Transhydrogenase antibody, Procollagen Proline 2 Oxoglutarate 4 Dioxygenase beta
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 64714
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid