PDIA2 Recombinant Rabbit Monoclonal Antibody (7H25L2), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Supplier: Thermo Scientific 700782
Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain. Recombit rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombit rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.PDI (ER marker) also known as protein disulfide isomerase is an enzyme present in the ER which plays a very important role in protein folding, by facilitating formation of correct disulphide bonds. Processing and maturation of the secretory proteins in the endoplasmic reticulum are actively done by the family of PDI proteins. This class of proteins show similar homology to the cytoplasmic protein thioredoxin. The protein catalyses the thiol/disulphide interchange interactions. Also depending upon the type of polypeptide substrate and redox potential, the protein brings about protein disulfide formation, isomerization or reduction.
|PBS with 0.09% sodium azide|
|Disulphide Isomerase antibody, GIT antibody, Glutathione Insulin Transhydrogenase antibody, Procollagen Proline 2 Oxoglutarate 4 Dioxygenase beta|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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