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PDIA2 Recombinant Rabbit Monoclonal Antibody (7H25L2), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Supplier:  Thermo Scientific 700782

Catalog No. PI700782


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Description

Description

Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain. Recombit rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombit rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

PDI (ER marker) also known as protein disulfide isomerase is an enzyme present in the ER which plays a very important role in protein folding, by facilitating formation of correct disulphide bonds. Processing and maturation of the secretory proteins in the endoplasmic reticulum are actively done by the family of PDI proteins. This class of proteins show similar homology to the cytoplasmic protein thioredoxin. The protein catalyses the thiol/disulphide interchange interactions. Also depending upon the type of polypeptide substrate and redox potential, the protein brings about protein disulfide formation, isomerization or reduction.
Specifications

Specifications

PDIA2
Recombinant Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide
Q13087
PDIA2
proprietary
100 μg
Primary
Human
Antibody
IgG
Western Blot
7H25L2
Unconjugated
PDIA2
Disulphide Isomerase antibody, GIT antibody, Glutathione Insulin Transhydrogenase antibody, Procollagen Proline 2 Oxoglutarate 4 Dioxygenase beta
Rabbit
Protein A
RUO
64714
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
SDS
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