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PDIR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 155451AP

Catalog No. 50-173-0303


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Description

Description

PDIR (protein disulfide isomerase-related protein) is a novel PDI protein that was originally isolated from a human placental cDNA library. It has been suggested that from its nucleotide sequence, PDIR has three CXXC-like motifs (Cys-Ser-Met-Cys, Cys-Gly-His-Cys and Cys-Pro-His-Cys), which are found in the PDI superfamily of proteins. The CXXC motif is responsible for oxidoreductase activity. PDIR is also shown to have a putative endoplasmic reticulum (ER) retention signal  ft.Lys-Glu-Glu-Leu ft. at its carboxyl terminus, indicative of ER resident proteins. Northern blot analysis of PDIR indicates that it is preferentially expressed in cells actively secreting proteins. It has also been shown that expression of PDIR is stress-inducible. Data suggest that PDIR, like other PDIs, has oxidoreductase activity of disulfide bonds and facilitates the protein folding process within the lumen of the ER.
Specifications

Specifications

PDIR
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q14554, Q5I0H9, Q921X9
PDIA5, PDIR, Protein disulfide isomerase A5
Rabbit
IgG
150 μL
-20°C
Primary
10954, 360722, 72599
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
PDIA5
Liquid
Pdia5
PDIR Fusion Protein Ag7901
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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