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PDK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 182621AP

Catalog No. 50-173-2076


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Description

Description

This antibody is specific to PDK1.

Serine/threonine kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
Specifications

Specifications

PDK1
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q15118, Q63065, Q8BFP9
PDH kinase 1, PDHK1, PDK1, Pyruvate dehydrogenase kinase isoform 1
Rabbit
IgG
150 μL
-20°C
Primary
116551, 228026, 5163
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PDK1
Liquid
PDK1
PDK1 Fusion Protein Ag13121
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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