PDX1 Mouse anti-Human, Clone:2G12, Abnova™

Mouse monoclonal antibody raised against partial recombinant human PDX1.

Supplier:  Abnova Corporation MAB17873

Catalog No. 89-334-363

Description

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq]

Specifications

• Antigen: PDX1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Flow Cytometry (1:200-1:400)
  Western Blot (1:100-1:500)
  The optimal working dilution should be determined by the end user.
• Gene: PDX1
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 2G12
• Description: pancreatic and duodenal homeobox 1
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1
• Immunogen: Recombinant protein corresponding to amino acids 39-283 of human PDX1.
• Gene ID (Entrez): 3651
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid