PDX1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 209891AP
DescriptionPDX1 (pancreas duodenum homeobox-1, also known as IPF-1, IDX-1, and STF-1) is a transcription factor that has been shown to activate insulin, glucokinase, IAPP, and somatostatin gene transcription. Significant interest surrounds this proteins glucose-dependent regulation of insulin gene transcription. Additionally, pdx-1 has been studied for its role in pancreatic development which includes maturation and differentiation of pancreatic precursor cells. Mutations in the pdx-1 gene have been shown to cause pancreatic agenesis, maturity-onset diabetes of the young, and type II diabetes.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Glucose sensitive factor, GSF, IDX 1, Insulin promoter factor 1, Insulin upstream factor 1, IPF 1, IPF1, Islet/duodenum homeobox 1, IUF 1, IUF1, MODY4, PDX 1, PDX1, STF 1|
|Antigen Affinity Chromatography|
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