Invitrogen™ PEAR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5112645

Catalog No. PIPA5112645

Description

PEAR1 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.

Specifications

• Antigen: PEAR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PEAR1
• Gene Alias: 3110045G13Rik; hPEAR1; Jagged and Delta protein; Jedi; Jedi-1; MEGF12; mPEAR1; Multiple EGF-like domains protein 12; multiple EGF-like-domains 12; multiple epidermal growth factor-like domains protein 12; Pear1; Platelet endothelial aggregation receptor 1; protein Jedi; RGD1305653; RP11-107D16.3
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 295293, 375033, 73182
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q5VY43, Q8VIK5
• Gene Symbols: PEAR1
• Immunogen: Recombinant Human Platelet endothelial aggregation receptor 1 protein (932-1037AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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