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PEG3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551298

Catalog No. PA551298


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Description

Description

The antibody detects endogenous levels of total PEG3 protein.

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5 ft. exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5 ft. exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
Specifications

Specifications

PEG3
Polyclonal
Unconjugated
PEG3
Liquid
PEG3
Synthetic peptide of human PEG3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.8 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q9GZU2
KIAA0287, ZSCAN24
Rabbit
IgG
100 μL
-20°C
Primary
5178
Documents
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