Peptidylarginine Deiminase Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5119333

Catalog No. PIPA5119333

Description

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.

Specifications

• Antigen: Peptidylarginine Deiminase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PADI1
• Gene Alias: HPAD10; hPAD-colony 10; PAD1; PADI1; PADI5; PDI; PDI1; PDI2; PDI3; PDI4; peptidyl arginine deiminase 1; peptidyl arginine deiminase, type I; peptidylarginine deiminase I; Protein-arginine deiminase type I; protein-arginine deiminase type-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29943
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q9ULC6
• Gene Symbols: PADI1
• Immunogen: Recombinant protein Peptidyl Arginine Deiminase Type I. The antigen corresponds to amino acid range 298-556 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG