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Thermo Scientific™ Perfluoroacylimidazoles (TFAI and HFBI) Acylation Reagents

Conduct acylation of hydroxyl groups and primary and secondary amines with the Thermo Scientific™ Perfluoroacylimidazoles (TFAI and HFBI).

$193.00

Specifications

For Use With FID and ECD
Standard Concentration 98 to 100%
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Products 1
Catalog Number Mfr. No. Standard Components Price Quantity & Availability  
Catalog Number Mfr. No. Standard Components Price Quantity & Availability  
PI44211
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Thermo Scientific™
TS44211
1-(2,2,3,3,4,4,4-Heptafluoro-1-oxobutyl)-1 H-imidazole
Each for $193.00
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Description

Description

Conduct acylation of hydroxyl groups and primary and secondary amines with the Thermo Scientific™ Perfluoroacylimidazoles (TFAI and HFBI). Compared to acid chlorides and anhydrides, the reactions of fluorinated acylimidazoles are smooth and quantitative, and produce no acid byproducts. The principal byproduct is imidazole, which is relatively inert. The volatile and stable fluoroacyl derivatives are ideal for FID and electron-capture detection (ECD) techniques.

Applications

Used in bifunctional derivatization schemes and in exchange reactions in which TMS derivatives are converted to HFB derivatives.

Hydroxyl groups of catecholamines are derivatized with TMSI, followed by conversion of the amines to acylamides with HFBI.

Tryptamine and metabolites present in spinal fluid have been analyzed by ECD using HFBI.

Specifications

Specifications

FID and ECD
98 to 100%
SDS

Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.

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