Invitrogen™ PEX3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537012

Catalog No. PIPA537012

Description

This antibody detects endogenous protein at a molecular weight of 42 kDa. Purity is >95% by SDS-PAGE.

Peroxin 3, also known as PEX3 (peroxisomal biogenesis factor 3) or TRG18, is a 373 amino acid multi-pass membrane protein that localizes to peroxisomes and belongs to the Peroxin family. Expressed ubiquitously, Peroxin 3 interacts with Peroxin 19 and is involved in peroxisome biosynthesis and membrane vesicle assembly, as well as in the maintenance of peroxisomal integrity. Additionally, Peroxin 3 acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Defects in the gene encoding Peroxin 3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both of which arise from a failure of peroxisomal protein import.

Specifications

• Antigen: PEX3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PEX3
• Gene Alias: 1700014F15Rik; 2810027F19Rik; 2900010N04Rik; PBD10A; Peroxin3; peroxin-3; peroxisomal assembly protein 3; peroxisomal assembly protein PEX3; Peroxisomal biogenesis factor 3; pex3; transformation-related protein 18; TRG18; zgc:56313
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56535, 83519, 8504
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P56589, Q9JJK4, Q9QXY9
• Gene Symbols: PEX3
• Immunogen: Synthetic peptide corresponding to amino acids 53-98 of human Peroxin 3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG