PEX5 Mouse anti-Canine, Human, Clone: OTI1D3, liquid, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene TA501389

Catalog No. 50-167-2531

Description

The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: PEX5
• Classification: Monoclonal
• Concentration: 0.74 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P50542
• Gene Alias: PBD2A, PBD2B, PTS1-BP, PTS1R, PXR1, RCDP5
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 100 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 486710, 5830

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1D3
• Conjugate: Unconjugated
• Gene: PEX5
• Format: Liquid
• Gene Symbols: PEX5
• Immunogen: Full length human recombit protein of human PEX5 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Canine, Human