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PEX5 Mouse anti-Canine, Human, Rat, Clone: OTI6E9, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA501430

Catalog No. 50-167-2574


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Description

Description

The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications

Specifications

PEX5
Monoclonal
0.57 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P50542, Q2M2R8
PBD2A, PBD2B, PTS1-BP, PTS1R, PXR1, RCDP5
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
312703, 486710, 5830
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI6E9
Unconjugated
PEX5
Liquid
PEX5
Full length human recombit protein of human PEX5 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Rat
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